I now nothing about Buffalo, but in my goat herd (ruminate) cocci can be a problem if not treated to the point that you get a good kill. Cocci has a hatch period of 15 days. Many of the treatments kill off the adult cocci but not the eggs. If you don't treat long enough to get the next hatch you will chase it. Treating for the 15 days ensures you get any hatch coming up. I have found that if I don't treat for 15 days the problem just comes back time after time and they grow slow. Cocci lives in the intestinal tract and robs nutrients from the animal. Scours are one of the many symptoms. I use 40% sulfadimethoxine and it works great. A call to the vet is worth the money as is a fecal test to determine just what you are dealing with. If it is a parasite at least you can identify it and go from there. As you probably already know wormers do not get cocci. You need a sulfa drug to kill them off.
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