Orthovisc is not going to work after just one injection.
About eight years ago my knee was so swollen that I couldn't get my pants over it. I was given a choice of knee joint replacement or injections. They were not too keen on recommending total joint replacement because as a mechanic they said it most likely would have to be redone in five to ten years.
I started a series of Hyalgan treatments (basically the same as Orthovisc, different manufacturer) series of five injections.I did not see much difference until after the third injection. After the fifth one things were much better and lasted for six months. The second series of five injections laasted nine months. The third series lasted two years. The next time they used Orthovisc, three injections rather than five. That lasted a year and then they switched to Synvisc. That again lasted a year. Last July I had another series of Synvisc and as of yet everything is feeling as good as it has since my original surgery in January 1971.
My knee has always been worse after the first two injections an any of series I have had. For me it usually take about two weeks after the third injection to feel the full benefits.
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