If by saying the wheels are "reversed" you mean they are dished in, like "()", then there's a pretty good chance it will fit on your trailer. 450 & M are same width except M has deep well rims that are not adjustable on the cast wheel. I hauled my M on a 81-1/2" wide trailer only reversing one wheel set about midway on the axle, had plenty of clearance between the fenders on the trailer.
If the wheels are dished in but set way out at the ends of the axles it should still fit.
The 450 used double bevel rims and have four different mounting positions on the cast wheel. There's a topic here about 560's that has the pages from the operators manual how to change position of the rims on the wheels, the 450 & 560 are very similar if not identicle.
When I hauled My M home I took everything necessary to reverse one wheel to narrow it up to get on my trailer, big floor jack, big 3/4" breaker bar and sockets. All stuff that would have been handy if I had problems along the road on the 200 mile trip.