"....but need a real good hit..."
Depends on the distance. At at 100-150 yards, the hit with a "maggie" doesn't have to be anything special. It will put them down. Stop and think about it for a minute.
Yes, a .22 Hornet is probably better than a .22 Magnum but a .223 is better than a Hornet and a 22/250 is better than a .223 and a 243 is better than a 22/250.