Get a good reloading manual, follow it to the letter. Where they list the "DO NOT EXCEED" loads, they mean it. Wise if you stay a few grains of the recommended powder lower than that. My experience - middle of the road about halfway between "start" and "DON'T" produces the best accuracy. Have always worked loads up from the bottom of the powder recommednations - a grain or so at a time - load a few, shoot a few... Load a few somewhat heavier... 'Course, I have a chronograph available, and a range here on the farm for testing purposes.
By the way, the brand name is "Nosler", a very good manufacturer of excellent bullets. Other than what I cast myself, almost everything I load is Nosler. Except Hornady XTP in my muzzleloader.