Hopefully the seller can load it for you so that won't be an issue. Once you get it home make sure that regardless of what you pick it with that the middle of the bed ways are supported. The worst thing you can do to a lathe is to pick it from the ends and let the middle hand free to sag. The longer the bed, the more important this is.
Now, once off the trailer, or out of the truck, if you've got a dirt floor I don't know what to tell you if you don't have a lift. Now if it's concrete, and it really needs to be to set a lathe on, use steel rollers. The milling machine I've got weights nearly 6000 lbs and I used about eight 1 1/2" diameter steel tubes to roll it from the door to it''s final resting place. With a couple of people it's not hard to do, but when doing it by yourself it's a real challange, to say the least.