Then look at it this way...The more connections you'll have the more chances you'll have that something will go wrong. More connections to keep clean and tight.
On the other hand...if you have the time and coils and just want to see if it'll work then go for it.
The motorcycle world was overrun with 6 volt coils many years ago. You'd have two 6 volt coils in one simple bracket for a cleaner installation. Just saying. :)
If you got some mad machinist skills you could engineer a second distributor on the other side of the engine. Use one distributor for cylinders 1 & 3. The other distributor for cylinders 2 & 4. At least, then, if one screwed up you could limp home on half your engine. N's will do that run on 2 cylinders thing.
Why mess with something that works? Because we can, that's why! You go Boler76! Get 'er done! :) :) :)