BTW,ALL great info so far !!! Glad to see people have knowledge and are not "guessing" on here!
Something else you can do that is helpful.If you have a GOOD timing light with the adjustable avance knob on the back of it(Like a Penske)and you know FOR A FACT your front crank hub and your pointer are set at TRUE zero,you can set your engine at different RPMS ad actually see where your advance is coming in at and what your total advance actually is.
Like has been said below,The MORE compression and the MORE advance you add to the engine ,the MORE critical it becomes.
In a REAL seroius race engine,we can actually "burn them down" with too much advance(Yea,melting pistons!!! )